16,388 research outputs found
Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study
Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to
assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA), cerebral oximetry (rSO2) and mean arterial pressure (MAP) during general
anaesthesia with a target controlled infusion.
Methods: A prospective, single-blinded and randomized study on adult patients scheduled for elective spine
surgery was carried out. After anaesthesia induction with propofol, remifentanil and rocuronium, when a stable BIS
value (45-55) was achieved, an automatic recording of BIS, SEF-95, rSO2 and MAP values during 9 min was
performed to establish patients baseline values. Subsequently, patients were randomly assigned to receive a
ketamine bolus dose of 0.2 mg/kg, 0.5 mg/kg or 1 mg/kg; all variables were recorded for additional 9 min after the
ketamine bolus, in the absence of any surgical stimulus. A p-value <0.05 was considered significant in the statistical
analysis.
Results and discussion: Thirty-nine patients were enrolled in the study. Our results show a dose-related
increase of SEF-95 and BIS values. DSA demonstrate a shift in the frequency range and power distribution towards
higher frequencies. Our results do not show significant differences in MAP and rSO2 values.
Conclusion: When ketamine is used intraoperatively in analgesic doses, the anaesthetist should anticipate an
increase in SEF-95 and BIS values which will not be associated with the level of anaesthesia.info:eu-repo/semantics/publishedVersio
Antisymmetric tensor propagator with spontaneous Lorentz violation
In this work, we study the spontaneous Lorentz symmetry breaking due to an
antisymmetric 2-tensor field in Minkowski spacetime. For a smooth quadratic
potential, the spectrum of the theory exhibits massless and massive
excitations. We show that the equations of motion for the free field obey some
constraints which lead to the massive mode be non-propagating at leading order.
Besides, there exists a massless mode in the theory which can be identified
with the usual Kalb-Ramond field, carrying only one on-shell degree of freedom.
The same conclusion holds when one analyses the pole structure of its Feynman
propagator. A new complete set of spin-type operators is found, which was the
requirement to evaluate the propagator of the Kalb-Ramond field modified by the
presence of a nonzero vacuum expectation value responsible for the Lorentz
violation.Comment: 13 pages. Some modifications to match published version in
EuroPhysics Letter
Irreversibility line and low-field grain-boundary pinning in electron-doped superconducting thin films
AC magnetic susceptibilities of electron-doped Pr_{1.85}Ce_{0.15}CuO_4 (PCCO)
and Sm_{1.85}Ce_{0.15}CuO_4 (SCCO) granular thin films have been measured as a
function of temperature and magnetic-field strength. Depending on the level of
homogeneity of our films, two different types of the irreversibility line (IL)
defined as the intergrain-loss peak temperature in the imaginary part of
susceptibility have been found. The obtained results are described via the
critical-state model taking into account the low-field grain-boundary pinning.
The extracted pinning-force densities in more granular SCCO films turn out to
be four times larger than their counterparts in less granular PCCO films
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